The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma

The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma

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Objective(s):Consumption of high-fat foods is one of the major causes of obesity.Physical exercise is a strategy used to counteract obesity.The aim of this study was to investigate the effect of eight weeks endurance training and high-fat diet (HFD) on appetite-regulating hormones in rat plasma.

Materials and Methods:Twenty eight iphone 14 price san francisco male Wistar rats were randomly divided into four groups: Control group with standard diet (CSD), endurance training with a standard diet (ESD), control group with high-fat diet (CHFD) and endurance training with high-fat diet (EHFD).Twenty-four hr after the last training session, the blood samples were obtained and analyzed for hormones levels.Results: The significant increased weight gain and food intake and decreased soiebiologique.com plasma nesfatin-1 and PYY3-36 levels were observed in CHFD group, while exercise under the HFD antagonized these effects.

There were no significant changes in ghrelin, insulin and leptin levels in different groups.Conclusion: These results suggest that exercise can prevent fattening effect of HFD.Probably, performing exercise makes a reduction of food intake and weight gain in rat via the increase in nesfatin-1 and PYY levels.

However, further studies are necessary to understand the exact mechanisms involved in this field.